Discovery of diverse human BH3-only and non-native peptide binders of pro-apoptotic BAK indicate that activators and inhibitors use a similar binding mode and are not distinguished by binding affinity or kinetics
BH3 Domains of BH3-Only Proteins Differentially Regulate Bax-Mediated Mitochondrial Membrane Permeabilization Both Directly and Indirectly - ScienceDirect
Epistatic mutations in PUMA BH3 drive an alternate binding mode to potently and selectively inhibit anti-apoptotic Bfl-1 | eLife
RCSB PDB - 6QFM: Structure of human Mcl-1 in complex with PUMA BH3 peptide
Apoptosis Initiated When BH3 Ligands Engage Multiple Bcl-2 Homologs, Not Bax or Bak | Science
BH3-mimetics: recent developments in cancer therapy | Journal of Experimental & Clinical Cancer Research | Full Text
Life | Free Full-Text | BH3-Only Proteins Noxa and Puma Are Key Regulators of Induced Apoptosis
PUMA BH3 -
BH3 Profiling: A Functional Assay to Measure Apoptotic Priming and Dependencies. - Abstract - Europe PMC
The Role of BH3-Only Proteins in Tumor Cell Development, Signaling, and Treatment - Rana Elkholi, Konstantinos V. Floros, Jerry E. Chipuk, 2011
Bim BH3, Peptide IV | Bim Peptide | MedChemExpress
Genome-Wide Prediction and Validation of Peptides That Bind Human Prosurvival Bcl-2 Proteins | PLOS Computational Biology